Spinach Artichoke Grilled Cheese

Featured in: Snack & Appetizer Ideas

This spinach and artichoke grilled cheese combines sautéed fresh spinach, tender artichoke hearts, and a blend of mozzarella, cream cheese, and Parmesan into a creamy, luxurious filling. Spread between buttered sourdough slices and pan-fried until golden brown with melted cheese oozing from the edges.

Perfect for vegetarian lunch or dinner, this elevated sandwich takes just 25 minutes from start to table. Serve alongside tomato soup for a classic pairing that's sure to satisfy.

Updated on Sun, 18 Jan 2026 14:51:00 GMT
Golden, crispy sourdough slices are stuffed with creamy spinach artichoke grilled cheese, melted mozzarella oozing from the edges. Save
Golden, crispy sourdough slices are stuffed with creamy spinach artichoke grilled cheese, melted mozzarella oozing from the edges. | circuitbites.com

My neighbor brought over leftover spinach dip one afternoon, and I stood at the counter eating it cold with crackers until I realized what I really wanted was that creamy, tangy filling melted between buttered bread. I grabbed sourdough from the freezer, shredded whatever cheese I had, and pressed the whole thing into a hot skillet. The smell alone made my husband wander into the kitchen asking what I was making for dinner. That improvised sandwich became a weekly request.

I made these sandwiches for my sister when she came over after a long shift at the hospital. She sat at the kitchen table still in her scrubs, too tired to talk much, and ate both halves without looking up. Halfway through, she just said, this is exactly what I needed. Sometimes the best meals are the ones that dont ask anything of you except to enjoy them.

Ingredients

  • Shredded mozzarella cheese: This is your melt, the cheese that pulls and stretches and holds everything together without overpowering the filling.
  • Cream cheese, softened: Let it sit on the counter for twenty minutes or youll be fighting lumps, it needs to blend smoothly into the greens.
  • Grated Parmesan cheese: The sharp, salty bite that keeps the sandwich from tasting flat or one note.
  • Unsalted butter, softened: Spread it thin and even on the bread so every inch turns golden and crisp in the pan.
  • Fresh spinach, chopped: I use baby spinach because it wilts fast and doesnt need trimming, just a rough chop after cooking.
  • Canned or jarred artichoke hearts, drained and chopped: Squeeze out extra brine or your filling will be watery, then chop them small so they mix in easily.
  • Small garlic clove, minced: One clove is enough, garlic can take over if you get heavy handed.
  • Sourdough bread: The tangy chew of sourdough balances the richness better than soft white bread ever could.
  • Salt: Just a pinch to wake up the spinach and artichoke without making the cheese taste salty.
  • Freshly ground black pepper: A few turns of the pepper mill adds a tiny bit of heat and depth.
  • Red pepper flakes (optional): I skip these when I make it for my kids, but I love the little pop of warmth they bring.

Instructions

Product image
Cook complete meals by frying, sautéing, simmering, and boiling with easy nonstick cleanup every day.
Check price on Amazon
Wilt the spinach:
Heat a medium skillet over medium heat, toss in the spinach with just a splash of water, and stir until it collapses into a bright green tangle. Press it in a mesh strainer or squeeze it in a clean towel to get rid of the liquid, or your filling will be soupy.
Mix the filling:
In a bowl, combine the drained spinach, chopped artichokes, cream cheese, mozzarella, Parmesan, garlic, salt, pepper, and red pepper flakes if using. Stir until everything is evenly distributed and the cream cheese has loosened into the mix.
Assemble the sandwiches:
Spread half the filling on each of two slices of sourdough, making sure to go all the way to the edges so every bite has flavor. Top with the remaining slices and press gently to help them stick.
Butter the outsides:
Use softened butter and spread it evenly across the outer faces of all four slices, this is what makes the bread turn golden and crunchy instead of pale and sad.
Grill until golden:
Heat a large nonstick skillet or griddle over medium heat, lay the sandwiches in carefully, and cook for 3 to 4 minutes per side, pressing lightly with a spatula. Flip when the bottom is deep gold and the cheese has started to soften.
Serve hot:
Pull them off the heat, slice each sandwich in half with a sharp knife, and serve while the cheese is still stretchy and warm.
Product image
Cook complete meals by frying, sautéing, simmering, and boiling with easy nonstick cleanup every day.
Check price on Amazon
A close-up shot shows the vibrant green spinach artichoke grilled cheese filling on toasted bread. Pin it
A close-up shot shows the vibrant green spinach artichoke grilled cheese filling on toasted bread. | circuitbites.com

One night I made these for a friend who was going through a breakup and didnt want to be alone. We sat on the floor with plates balanced on our knees, and she told me she forgot food could taste this good when youre sad. I didnt say much, just made her another one. Sometimes comfort isnt about the words, its about the butter and the cheese and the quiet company.

Choosing Your Bread

Sourdough is my go to because the tanginess cuts through the richness of the cheese, but Ive used everything from ciabatta to whole wheat when thats what I had on hand. Avoid anything too soft or it will get soggy under the weight of the filling. A sturdy bread with a good crust will hold up to the heat and give you that satisfying crunch.

Making It Ahead

You can mix the filling a day in advance and keep it covered in the fridge, then just assemble and grill when youre ready to eat. I wouldnt build the sandwiches ahead of time because the bread will absorb moisture and lose its crispness. If you have leftover filling, spread it on crackers or use it as a dip, it keeps for three days.

Serving Suggestions

I almost always serve these with a simple tomato soup, the acidity and sweetness of the soup plays perfectly against the creamy, savory sandwich. A handful of greens dressed in lemon and olive oil on the side makes it feel like a real meal instead of just melted cheese on bread.

  • Pair with a crisp dill pickle for a little brightness and crunch.
  • Serve alongside a light arugula salad with balsamic vinaigrette.
  • Pour a glass of cold white wine or sparkling water with lemon to balance the richness.
Product image
Blend soups, smoothies, sauces, and baby food directly in pots for quick, smooth results.
Check price on Amazon
Perfect for lunch, this spinach artichoke grilled cheese pairs wonderfully with a warm bowl of tomato soup. Pin it
Perfect for lunch, this spinach artichoke grilled cheese pairs wonderfully with a warm bowl of tomato soup. | circuitbites.com

This sandwich has become my answer to the question of what to make when I want something that feels indulgent but doesnt require much effort. Its proof that sometimes the best meals come from mixing what you love into something you already know how to make.

Frequently Asked Questions

Can I prepare the spinach-artichoke filling ahead of time?

Yes, you can prepare the filling up to 24 hours in advance. Store it in an airtight container in the refrigerator. Simply assemble and cook the sandwiches when ready to serve.

What bread alternatives work best for this sandwich?

While sourdough provides excellent tang and crispness, whole wheat, multigrain, ciabatta, or Texas toast all work wonderfully. Choose bread that's sturdy enough to hold the creamy filling without becoming soggy.

How do I prevent the filling from leaking out while cooking?

Spread the filling evenly but not too thickly, leaving a slight border around the bread edges. Don't overstuff the sandwich, and press gently with your spatula while cooking rather than pressing hard.

Can I add meat to make this more filling?

Absolutely. Crispy bacon, prosciutto, or diced ham complement the spinach and artichoke beautifully. Layer the meat between the filling and bread before cooking.

What temperature should my skillet be for the perfect golden crust?

Medium heat is ideal. Too high and the bread burns before the cheese melts; too low and the bread absorbs butter without browning. Watch for a gentle sizzle when the sandwich hits the pan.

Can frozen spinach work instead of fresh?

Yes, use thawed and thoroughly drained frozen spinach. Squeeze out excess moisture in a clean kitchen towel to prevent a watery filling that could make the sandwich soggy.

Spinach Artichoke Grilled Cheese

Golden sourdough sandwich stuffed with creamy spinach, artichoke hearts, and melted mozzarella. A gourmet comfort food classic.

Prep Time
15 Minutes
Cook Time
10 Minutes
Total Time
25 Minutes


Difficulty: Easy

Cuisine: American

Yield: 2 servings

Dietary: Vegetarian

Ingredients

Dairy

01 1 cup shredded mozzarella cheese
02 1/2 cup cream cheese, softened
03 1/4 cup grated Parmesan cheese
04 2 tablespoons unsalted butter, softened

Vegetables

01 1 cup fresh spinach, chopped
02 1/2 cup canned or jarred artichoke hearts, drained and chopped
03 1 small garlic clove, minced

Bread

01 4 slices sourdough bread

Seasonings

01 1/4 teaspoon salt
02 1/8 teaspoon freshly ground black pepper
03 Pinch of red pepper flakes, optional

Instructions

Step 01

Prepare spinach: In a medium skillet over medium heat, add spinach and a splash of water. Sauté for 1 to 2 minutes until wilted. Drain excess moisture thoroughly.

Step 02

Blend filling: In a bowl, combine sautéed spinach, chopped artichoke hearts, cream cheese, mozzarella, Parmesan, garlic, salt, pepper, and red pepper flakes if using. Mix until well blended.

Step 03

Assemble sandwiches: Spread the spinach-artichoke mixture evenly onto two slices of sourdough. Top with the remaining bread slices to form sandwiches.

Step 04

Butter bread: Butter the outsides of the bread slices generously on all sides.

Step 05

Cook sandwiches: Heat a large nonstick skillet or griddle over medium heat. Place sandwiches in the skillet and cook for 3 to 4 minutes per side, pressing gently, until bread is golden brown and cheese is melted.

Step 06

Serve: Remove from heat, slice in half, and serve immediately.

Tools You'll Need

  • Medium skillet
  • Mixing bowl
  • Spatula
  • Nonstick skillet or griddle
  • Knife

Allergy Information

Please check ingredients for potential allergens and consult a health professional if in doubt.
  • Contains milk from cheese and butter
  • Contains wheat from sourdough bread
  • May contain traces of soy or nuts depending on bread and cheese brands

Nutrition Facts (Per Serving)

It is important to consider this information as approximate and not to use it as definitive health advice.
  • Calories: 430
  • Total Fat: 24 g
  • Total Carbohydrate: 39 g
  • Protein: 16 g